You're all overlooking one tiny little detail.
To me, this isn't a flying car; it's a flying machine that also happens to be roadworthy. What's more, the helicopter parts *fold up* into the car at the push of a button. It's a difference, but a very slight one. You probably couldn't just take to the skies while you're on the road…I imagine you'd have to stop first and then unfold everything. But just think about it! Our heroes could take that folded-up thing and shove it right in the back of the ECTO-1 with minimal fuss. And then, if they needed to, they could drag it out, deploy the air gear, and up-up-and-away.
Hmm…While we're on the subject of flying Ghostbusting vehicles, I had an epiphany about the Ecto-Bomber over the weekend. It looks very much like an adaptation of a racing plane called the Gee Bee (G.B., geddit?).