If you wrote a darker kind of Ghostbusters, that article wouldn't be as good as an original idea of Ghostbusters. The fact that, GB came out and the show was a comedy. There were little jokes and side puns fit into every situation. Even the movie had its share of fun and comedy. If you are going to make a story of blood and guts you are going to have to explain as to how the bodies got to be so horrible. Ghosts can slime you, and effect your mental ability to think.
In conclusion, you want to entertain the reader more than scare them. You also want to excite them with your big words of science and technology.
ORACAL G